transgenic mice
转基因小鼠
2025-01-06 21:10 浏览次数 1
转基因小鼠
in other experiments, they discovered that 「knocking」 out the gene that produces sp in transgenic mice lowered their chances of acquiring the condition.
在其他的实验里,他们发现在转基因白鼠中,剔除那些制造「sp」物质的基因会降低他们得到那种疾病的概率。
therefore, we assessed adenosine levels and selective ar expression in transgenic mice with left ventricular systolic dysfunction secondary to overexpression of tumor necrosis factor- (tnf 1.6).
因此,我们检测了左心室收缩功能障碍并继发肿瘤坏死因子(tnf1.6)过表达的转基因老鼠腺苷水平和选择性ar的表达。
as for the two transgenic mice who didn「t do so well, the researchers speculate that they didn」t have a good mix of the different photopigments in their eyes.
其余2/5基因突变的老鼠做的没有这么好,研究推测可能由于在它们眼中的不同的感光色素没有很好的混合。
in contrast, the transgenic mice exhibited a marked insulin resistance as revealed by the insulin tolerance test, as well as significantly higher basal serum insulin levels.
采用高脂食物喂养时,转基因小鼠发生显性糖尿病,但对照小鼠未发生显性糖尿病。
in addition, transgenic mice performed normally in learning and memory in both place navigation training and the 1st spatial probe test.
在定位航行训练和第一次空间探索测试中,两组鼠在训练时逃避潜伏期及测试中在目标象限探索时间无统计学差异;
the selected sequences are tested for biological function by their activation of t-cells of hla transgenic mice and of pathogen infected subjects.
选定的序列通过激活hla转基因鼠的t-细胞和感染的受试者病原菌来检测其生物学功能。
they used three types of mice to test their hypothesis: wild-type (wt) mice, transgenic mice that do not express any gm-scf (gm-/-), and transgenic mice that express gm-scf only in the lung (spc-gm).
他们应用三型小鼠去试验他们的假设:野生-型(wt)小鼠,不能表达任何gm-scf转基因小鼠(gm-/-),,和只能在肺表达gm-scf的转基因小鼠(spc-gm)。
it is proved that the conformity site of exogenous gene in app transgenic mice is random, the tumor induced by gene conformity site could manifest with different stage of cell growing.
结论证实了转基因动物导入外源性基因整合位点是随机的;整合位点引起的肿瘤可以随着细胞发育的不同阶段,逐渐的显现。
we also found positive transgenic mice in the kidney and spleen tissues of 5-lo, flap protein expression was significantly higher than normal mice by immunohistochemistry.
免疫组织化学等方法分析得到在转基因阳性鼠肾、脾组织中5-lo、flap蛋白的表达明显高于正常鼠。
the researchers tested transgenic mice that spontaneously develop ibd and then progress to colitis-associated colon cancer, producing the human version of muc1 in both disease states.
研究者利用ibd自发转基因小鼠来进行试验,随后这些小鼠进展为肠炎相关性结肠癌,两种疾病均可产生异常增生的人类muc1蛋白。
methods: app transgenic mice of same age and app positive control(divided in groups of difference by dosage) were selected to perform water maze and jump platform experiments.
方法:选用同龄转基因app阳性动物(不同用药组)做水迷宫和跳台实验。
the present invention also relates to a method of generation of fully functional heavy chain-only antibodies in transgenic mice in response to antigen challenge.
本发明还涉及在转基因小鼠中响应抗原激发产生全功能性仅有重链的抗体的方法。
objective construction of transgenic mice with selective brain overexpression of kynureninase(kynu) to investigate the effect of increased kynu activity on blood pressure(bp).
目的本研究旨在构建脑组织选择性过表达犬尿氨酸酶(kynu)的转基因小鼠,在整体水平研究kynu活性增强对血压的影响。
aim: to study the multi-lineage potential of adipose tissue-derived stromal cells(adscs) from transgenic mice with green fluorescent protein(gfp) gene.
目的:研究绿色荧光蛋白(gfp)转基因小鼠脂肪间充质干细胞(adsc)体外定向诱导下的多向分化潜能。
we also established the cell line of this transgenic mice model through primary cell culture to make use this model more efficiently.
为了更为有效地利用该模型小鼠,我们通过原代培养建立了该模型的肿瘤细胞系。
objective to observe the learning and memory function and ultrastructure in hippocampus of app/ps1 double transgenic mice with alzheimer′s disease(ad).
目的观察app/ps1双转基因阿尔茨海默病小鼠的记忆功能与超微病理改变。
conclusion trpv1 transgenic mice have been established successfully. the model will contribute to the further research of the physiological function of trpv1.
结论成功建立了trpv1转基因小鼠模型,为深入研究trpv1的功能提供了更好的条件。
as detected by western blotting, trpv1 expressions in the brain and skeletal muscle of the transgenic mice were significantly higher than the wild-type littermates.
经蛋白免疫印记法证实,与同窝野生型小鼠相比,转基因小鼠的脑组织和肌肉组织中trpv1的表达显着升高。
methods 3month old app695 transgenic mice were randomly divided into model and yizhi treatment groups, and negative transgenic mice were selected into normal control group.
方法app695转基因小鼠分为ad模型组和益智汤治疗组,同月龄同背景转基因阴性小鼠为正常对照组。
objective to construct heparin-binding epidermal growth factor-like growth factor transgenic mice in order to investigate the role of hb-egf in the fibrosis of tissues.
目的建立系统表达肝素结合性表皮生长因子的转基因动物模型,利用转基因动物模型研究hb-egf与组织纤维化的关系。
myocardial infarction was produced by coronary ligation in a20 transgenic mice and control animals.
利用冠脉结扎使a20基因小鼠和对照组小鼠产生心肌梗死。
no significant difference was measured in the frequency of sepscs and mepscs. however, compared to the wild type mice, transgenic mice exhibited augmented amplitude of sepscs and mepscs.
在突触传递中,野生型鼠与转基因鼠的自发兴奋性突触后电流和微小兴奋性突触后电流的幅度差异显着,而频率没有显着性差异;
「the muscle from the pgc-1a transgenic mice was strikingly redder in appearance than wild-type controls, 」 indicative of their increased mitochondrial content, the researchers now report.
研究者报告说:「来自pgc-1a转基因小鼠的肌肉比野生型对照组的明显发红,这是其中线粒体更丰富的表现。」