The aim of the exprements is to investigate RH-01's inhibition to HOS cell in vitro and to transplantable tumor in mice, and to discuss basically its mechanism of action.
本实验目的:本实验进一步研究RH-01对体外培养的人源骨肉瘤HOS细胞和动物移植性肿瘤的抑制作用及特点,并初步探讨其作用机制。
Pathohistology showed that the structure of the transplantable tumor was similar to that of the original human tumor.
裸鼠移植瘤病理组织学的结构与原始人体肿瘤的形态相似。
Methods: Inhibitory effects of FAC were investigated on the transplantable tumor models of H22 and L1210 in mice.
方法:采用移植性小鼠肝癌H 22、移植性小鼠白血病l 1210为模型,观察FAC体内抗肿瘤作用。
Successful establishment of transplantable tumor models should satisfy the following standards: 15 - 20 successive generations (at least 3 - 4 animals each generation);
移植瘤建成的标準是:传代数应在15-20代(每代传3—4只动物);